For cells that are easily lysed, the DNA denaturation step included in the protocol for the phi29-XT WGA Kit is sufficient. However, for cells that are difficult to lyse, DNA extraction may be beneficial. The Monarch^® Genomic DNA Purification Kit (NEB #T3010) can be used to extract DNA from a broad range of sample types, such as cells, blood, tissue, bacteria, yeast, saliva, and swabs.